BiTherapca Health

When you eat, food is either burnt down, or is stored as fat, if in excess. If our metabolism is high, we burn food faster. High metabolism can be due to properly functioning thyroid, good immune system, properly functioning brain or physical activity. When we continue to eat more, we store excess food as fat and this storage is promoted by insulin. Fat, especially cholesterol, lodges in blood vessels, causing them to narrow down and this leads to hypertension, setting the stage for stroke and heart attack. Pretty soon fat cells become saturated with fat and, because of this, insulin no longer promotes glucose uptake into cells and its subsequent conversion into fat, as these cells run out of storage space. This is called insulin resistance. Exercise will will burn down fat and create more storage space for glucose uptake. Excess fat also impairs protein, and hence insulin, synthesis. Eventually, excess glucose damages insulin secreting cells in the pancreas and this further redu...

People have witnessed extreme irritability, anxiety, depression, deterioration of mental acuteness(sharpness), as well as a general decline in their physical well-being, with long term sleep deprivation. The biological clock in sleep is well regulated by the body, but sometimes things go awry, for some reasons, not only limited to health but also to factors such as the nature of our jobs. The human catabolism, which is the wear and tear of tissue, and the digestion and breakdown of assimilated food to supply energy, takes place mainly during the day, when the body cells are more active as we eat, work through thinking and moving our body parts, walk, play and as our body organs toil against all adversity. Catabolic activity peaks in the late afternoon; this is when we have maximum food breakdown and enzymatic processing of cellular debris to be later cleared by phagocytes. Immune activity sets in, as physical and mental activities wane, and incrementally progresses into the night...

Cancer cells have altered genetic material and sometimes associated proteins called histones and have lost control of cell division. The telomeres have shortened in length through damage. Genes for repairs, found in telomeres, have been damaged. Repair does not match the damage because stress is too metabolically demanding to the cell. Telomeres grow back by some repair mechanism that could not take place during the metabolically demanding damage to the cell. The regrowth in telomeres means that the change in the cell has been consolidated and so can be perpetuated as cancer cells multiply uncontrollably. Treatment with cytotoxic drugs and radiation further damages the cancer cells, shortens their telomeres and leads to cell death. Other treatments attempt to put a brake on excessive cell division. Still others target hormones that promote cell growth(division) via cell receptors (transcription factors). Continuous cell, and hence DNA, damage, indirectly from excessive cell stimu...