Maintaining a Healthy Metabolism
Metabolism involves catabolism and anabolism. These two usually go in tandem such that as there is more breakdown of food, there is a complementary buildup of tissue. Tissue breakdown in autophagy supplies the nutrients and energy, necessary for tissue recycling and rejuvenation, through the intermediary of growth factors and the growth hormone. However, dietary food supply provides excessive amount of carbohydrates and fats that breakdown to form de novo fat, which through insulin, is stored and in addition to tissue buildup from available amino acids from dietary protein. High AMP prevents metabolism due to inability of enzymes, principally tyrosine kinases, to phosphorylate target proteins and DNA and ramp up metabolism. AMP synthetase, in response, goes into action to promote autophagy, the breakdown of tissue proteins, and stored carbohydrates and lipids, and ramp up metabolism. This is a compensatory mechanism that coincides with the activation of adenylate cyclase which now p...