BiTherapca Health

Energy supply is the driver of metabolic activities and sustainability of life. It is no surprise, therefore, that development, growth, mental and physical acivities all rely on an adequate, ready-to-use energy source, the ATP. Since the mitochondrion is the major source of this, its well-being lies at the root of optimal body function and its poor state at the heart of most diseases. Mitochondrial gene expression is conditioned by the peroxisome proliferation genes, driven by factors such as, fibrate drugs, free fatty acids and arachidonic acids. Peroxisome activated receptors form heterodimers with vitamins A and D receptors. It goes without saying that any stress, such as sudden nutritional overload from food intake; exercise, fasting, with energy exhaustion or low supplies that call for mobilization from stores, activates the peroxisome proliferator-activated receptor, increases mitochondrial function and promotes metabolism. The receptors are nuclear genes that upregulate mitoch...